Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 10/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HTR1A | P08908 | 2/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | HTR3A | P46098 | 1/20 | 0.64 |
| ▸ | BACE1 | P56817 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NOS3 | P29474 | 2/20 | 0.50 |
| ▸ | NOS1 | P29475 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10488347 | 0.97 | BLM (0.65) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| SCHEMBL224548 | 0.85 | TAAR1 (0.72) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| SCHEMBL5025570 | 0.84 | MAOA (0.50) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| SCHEMBL196989 | 0.83 | TAAR1 (0.64) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| SCHEMBL2325226 | 0.82 | MAOA (0.60) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL3168355 | 0.82 | BLM (0.74) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| Iodide SCHEMBL29101247 | 0.82 | TAAR1 (0.68) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| SCHEMBL7539245 | 0.82 | CHKA (0.58) | TDP1NOS3NOS1MAOB | |
| Hydrochloric Acid SCHEMBL3668004 | 0.82 | BLM (0.74) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| SCHEMBL1049854 | 0.79 | HTR2A (0.60) | TAAR1KDM4EALDH1A1HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670305-B2 | Polyurethane dispersant and the method for its preparation | Wang, Zhijun (CN) | 2017-06-06 | — | — | US | claimed |
| EP-2839873-B1 | POLYURETHANE DISPERSANT AND PREPARATION METHOD THEREOF | WANG ZHIJUN (CN) | 2017-01-04 | — | — | EP | claimed |
| US-20150065676-A1 | POLYURETHANE DISPERSANT AND THE METHOD FOR ITS PREPARATION | AFCONA CHEMICALS (HAIMEN) CO., LTD. (CN) | 2015-03-05 | — | — | US | claimed |
| EP-2839873-A1 | POLYURETHANE DISPERSANT AND PREPARATION METHOD THEREOF | Wang, Zhijun (CN) | 2015-02-25 | — | — | EP | claimed |
| EP-3555105-A1 | 7-PHENYLETHYLAMINO-4H-PYRIMIDO[4,5-D][1,3]OXAZIN-2-ONE COMPOUNDS AS MUTANT IDH1 AND IDH2 INHIBITORS | Eli Lilly and Company (US) | 2019-10-23 | — | — | EP | disclosed |
| EP-3464281-A1 | MUTANT IDH1 INHIBITORS | Eli Lilly and Company (US) | 2019-04-10 | — | — | EP | disclosed |
| WO-2018111707-A1 | 7-PHENYLETHYLAMINO-4H-PYRIMIDO[4,5-D][1,3]OXAZIN-2-ONE COMPOUNDS AS MUTANT IDH1 AND IDH2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2018-06-21 | — | — | WO | disclosed |
| WO-2017213910-A1 | MUTANT IDH1 INHIBITORS | ELI LILLY AND COMPANY (US) | 2017-12-14 | — | — | WO | disclosed |
| US-9670305-B2 | Polyurethane dispersant and the method for its preparation | Wang, Zhijun (CN) | 2017-06-06 | — | — | US | disclosed |
| EP-2839873-B1 | POLYURETHANE DISPERSANT AND PREPARATION METHOD THEREOF | WANG ZHIJUN (CN) | 2017-01-04 | — | — | EP | disclosed |
| US-20150152476-A1 | REAGENTS AND METHODS FOR DIRECT LABELING OF NUCLEOTIDES | MARKER GENE TECHNOLOGIES, INC. | 2015-06-04 | — | — | US | disclosed |
| US-20150065676-A1 | POLYURETHANE DISPERSANT AND THE METHOD FOR ITS PREPARATION | AFCONA CHEMICALS (HAIMEN) CO., LTD. (CN) | 2015-03-05 | — | — | US | disclosed |
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-12-02 | — | — | US | disclosed |
| WO-2004024702-A1 | NOVEL CARBOXAMIDE COMPOUNDS HAVING AN MCH-ANTAGONISTIC EFFECT, MEDICAMENTS CONTAINING SAID COMPOUNDS, AND METHODS FOR THE PRODUCTION THEREOF | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-03-25 | — | — | WO | disclosed |
| US-5250426-A | Catalytic hydrolysis using monoclonal antibodies | THE SCRIPPS RESEARCH INSTITUTE (US) | 1993-10-05 | — | — | US | disclosed |
| US-4873254-A | ADRENERGIC BLOCKING AGENTS OR CALCIUM CHANNEL BLOCKERS; HYPOTENSIVE AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-10-10 | — | — | US | disclosed |
| EP-0194751-A1 | Dihydropyridine alkanol amines, process for their preparation and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-09-17 | — | — | EP | disclosed |
| US-4598077-A | Amidine derivatives and cardiotonic compositions | TORII & CO. LTD. (JP) | 1986-07-01 | — | — | US | disclosed |
| US-4158063-A | Acylamino(alkyl)benzene derivatives and process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-12 | — | — | US | disclosed |
| US-4136197-A | HYPOGLYCAEMICALLY AND HYPOLIPIDAEMICALLY EFFECTIVE N-SUBSTITUTED CARBOXYLIC ACID AMIDES | BOEHRINGER MANNHEIM GMBH (DE) | 1979-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | MCHR2, MCHR1, NPY1R | TAAR1 141/4885KDM4E 492/4885ALDH1A1 3363/4885 |
| US-20150152476-A1 | REAGENTS AND METHODS FOR DIRECT LABELING OF NUCLEOTIDES | DUT, DNTT, NUDT1 | TAAR1 4268/4885KDM4E 2892/4885ALDH1A1 1343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.