Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HTR1A | P08908 | 2/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | HTR3A | P46098 | 1/20 | 0.64 |
| ▸ | BACE1 | P56817 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5968428 | 0.87 | TAAR1 (0.50) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| SCHEMBL40656 | 0.85 | CA2 (0.77) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| SCHEMBL224548 | 0.85 | TAAR1 (0.72) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| SCHEMBL1049854 | 0.84 | HTR2A (0.60) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| SCHEMBL1936040 | 0.83 | TAAR1 (0.64) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| SCHEMBL632532 | 0.83 | CA2 (0.59) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| SCHEMBL6051 | 0.83 | GFER (0.68) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| SCHEMBL2361398 | 0.82 | MAOA (0.60) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| SCHEMBL10451946 | 0.82 | HTR2A (0.59) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| SCHEMBL6057959 | 0.82 | CA2 (0.72) | KDM4EALDH1A1BACE1TDP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2895517-B1 | TWO-COMPONENT POLYURETHANE COMPOSITION | SIKA TECH AG (CH) | 2020-12-16 | — | — | EP | claimed |
| US-20150259465-A1 | TWO-COMPONENT POLYURETHANE COMPOSITION | SIKA TECHNOLOGY AG (CH) | 2015-09-17 | — | — | US | claimed |
| EP-2895517-A1 | TWO-COMPONENT POLYURETHANE COMPOSITION | Sika Technology AG (CH) | 2015-07-22 | — | — | EP | claimed |
| CN-104640894-A | Two-component polyurethane composition | SIKA TECHNOLOGY AG | 2015-05-20 | — | — | CN | claimed |
| CN-101687775-B | Aldimines and compositions comprising aldamine | SIKA TECHNOLOGY AG | 2015-05-06 | — | — | CN | claimed |
| CN-101765583-B | Aldimines comprising hydroxyl groups, and compositions containing aldimine | SIKA TECHNOLOGY AG | 2014-06-04 | — | — | CN | claimed |
| CN-102224181-B | Aldimine and composition containing aldimine | SIKA TECHNOLOGY AG | 2014-04-30 | — | — | CN | claimed |
| WO-2014040922-A1 | TWO-COMPONENT POLYURETHANE COMPOSITION | SIKA TECHNOLOGY AG (CH) | 2014-03-20 | — | — | WO | claimed |
| EP-2706073-A1 | Two-component polyurethane composition | Sika Technology AG (CH) | 2014-03-12 | — | — | EP | claimed |
| US-8455100-B2 | Aldimines comprising hydroxyl groups, and compositions containing aldimine | SIKA TECHNOLOGY AG (CH) | 2013-06-04 | — | — | US | claimed |
| EP-2030965-A1 | Aldehydes containing hydroxyl groups | Sika Technology AG (CH) | 2009-03-04 | — | — | EP | claimed |
| EP-2030967-A1 | Aldimines containing hydroxyl groups and compositions containing aldimine | Sika Technology AG (CH) | 2009-03-04 | — | — | EP | claimed |
| WO-2009010522-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDAMINE | SIKA TECHNOLOGY AG (CH) | 2009-01-22 | — | — | WO | claimed |
| EP-2017260-A1 | Aldimines and compounds containing aldimine | Sika Technology AG (CH) | 2009-01-21 | — | — | EP | claimed |
| US-20080280145-A1 | moisture-reactive hot-melt adhesive which comprises at least one aldimine and at least one polyurethane polymer ( polyesterurethane copolymer, polyetherurethane copolymer)which contains isocyanate groups and is solid at room temperature; bonded assembly is notable for improved adhesive | SIKA TECHNOLOGY AG (CH) | 2008-11-13 | — | — | US | claimed |
| EP-1990387-A1 | Composite layer body joined with polyurethane holt melt glue and method for gluing plastics containing dilutents | Sika Technology AG (CH) | 2008-11-12 | — | — | EP | claimed |
| WO-2008116928-A1 | ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN | SIKA TECHNOLOGY AG (CH) | 2008-10-02 | — | — | WO | claimed |
| EP-1975190-A1 | Aldimines with reactive groups containing active hydrogen | Sika Technology AG (CH) | 2008-10-01 | — | — | EP | claimed |
| WO-2008052999-A1 | POLYURETHANE COMPOSITION WITH GOOD INITIAL STRENGTH | SIKA TECHNOLOGY AG (CH) | 2008-05-08 | — | — | WO | claimed |
| EP-1918314-A1 | Polyurethane composition with high green strength | Sika Technology AG (CH) | 2008-05-07 | — | — | EP | claimed |