Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 15/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360566 | 0.87 | RORC (0.58) | RORC | |
| SCHEMBL19360651 | 0.85 | KMT2A (0.43) | KMT2ARORCCHRM3MAPTENPP2 | |
| SCHEMBL19360568 | 0.79 | RORC (0.61) | RORC | |
| SCHEMBL19360569 | 0.77 | RORC (0.57) | RORC | |
| SCHEMBL19360597 | 0.77 | RORC (0.61) | RORC | |
| SCHEMBL19360649 | 0.77 | RORC (0.43) | KMT2ARORCMAPT | |
| SCHEMBL19360600 | 0.76 | RORC (0.51) | RORC | |
| SCHEMBL19360641 | 0.75 | ALDH1A1 (0.48) | KMT2AMAPTENPP2 | |
| SCHEMBL19360642 | 0.73 | RORC (0.61) | KMT2ARORCMAPT | |
| SCHEMBL20631881 | 0.72 | RORC (0.73) | RORCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |