Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445908 | 0.86 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL22624054 | 0.80 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL20274346 | 0.76 | — | — | |
| SCHEMBL11911322 | 0.73 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL11032985 | 0.73 | LMNA (0.35) | ALDH1A1 | |
| SCHEMBL14561703 | 0.67 | — | — | |
| SCHEMBL15274248 | 0.67 | — | — | |
| SCHEMBL2297967 | 0.67 | — | — | |
| SCHEMBL23667242 | 0.67 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL12013955 | 0.67 | ALDH1A1 (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2884982-B1 | SUBSTITUTED PHENYL SPLEEN TYROSINE KINASE (Syk) INHIBITORS | MERCK SHARP & DOHME (US) | 2017-09-20 | — | — | EP | disclosed |