SCHEMBL11032985

SCHEMBL11032985

COC(C)(C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
F2 P00734 1/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11911322 0.79 ALDH1A1 (0.35) ALDH1A1
SCHEMBL8445908 0.78 ALDH1A1 (0.40) ALDH1A1
Perflenapent SCHEMBL5186220 0.75 LMNA (0.47) LMNAF2PRSS1PRSS2PRSS3
SCHEMBL22624054 0.73 ALDH1A1 (0.35) ALDH1A1
SCHEMBL19361069 0.73 ALDH1A1 (0.35) ALDH1A1
SCHEMBL23667242 0.72 ALDH1A1 (0.30) ALDH1A1
Perflubutane SCHEMBL5188622 0.71 LMNA (0.41) LMNAF2PRSS1PRSS2PRSS3
SCHEMBL22471718 0.71 LMNA (0.38) LMNA
SCHEMBL1687065 0.71 LMNA (0.38) LMNAF2PRSS1PRSS2PRSS3
SCHEMBL21879331 0.71 LMNA (0.38) LMNAF2PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59112936-A None JP disclosed
JP-S59112936-A PERFLUOROETHER COMPOUND AND ITS PREPARATION GREEN CROSS CORP:THE 1984-06-29 JP disclosed