Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17897787 | 0.80 | CHRM2 (0.41) | KDM4EALDH1A1HSD17B10NTRK1LMNA | |
| SCHEMBL14397210 | 0.79 | GAA (0.45) | KDM4EALDH1A1TSHRHSD17B10MAPK1 | |
| SCHEMBL22837272 | 0.73 | NTRK1 (0.45) | KDM4EALDH1A1TSHRHSD17B10NTRK1 | |
| SCHEMBL14397205 | 0.71 | ALDH1A1 (0.42) | KDM4EALDH1A1HSD17B10NTRK1LMNA | |
| SCHEMBL14397606 | 0.67 | ALDH1A1 (0.51) | KDM4EALDH1A1TSHRNTRK1HPGD | |
| SCHEMBL9124136 | 0.67 | KDM4E (0.58) | KDM4EALDH1A1TSHRHSD17B10MAPK1 | |
| SCHEMBL8480082 | 0.67 | KMT2A (0.49) | KDM4EALDH1A1TSHRHSD17B10MAPK1 | |
| SCHEMBL9394723 | 0.66 | CDK4 (0.57) | KDM4EALDH1A1HSD17B10NTRK1LMNA | |
| SCHEMBL8412387 | 0.66 | HTR6 (0.65) | KDM4EALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL31486077 | 0.66 | ALDH1A1 (0.57) | KDM4EALDH1A1TSHRHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9768383-B2 | Method for applying an organic semiconductor layer based on epindolidione to a carrier | UNIVERSITAET LINZ (AT) | 2017-09-19 | — | — | US | disclosed |