Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19365248 | 0.90 | MCHR1 (0.41) | MCHR1EPHB4MEN1POLBKMT2A | |
| SCHEMBL16776315 | 0.85 | MCHR1 (0.41) | MCHR1EPHB4MEN1POLBKMT2A | |
| SCHEMBL16238014 | 0.81 | MEN1 (0.38) | MCHR1MEN1POLBKMT2AGRIN2B | |
| SCHEMBL19365694 | 0.79 | CHRM3 (0.45) | MEN1KMT2A | |
| SCHEMBL19365423 | 0.78 | MCHR1 (0.44) | MCHR1GAAMEN1KMT2AGRIN2B | |
| SCHEMBL19365414 | 0.77 | MCHR1 (0.45) | MCHR1GAATRPV1GRIN2B | |
| SCHEMBL20632390 | 0.76 | MCHR1 (0.35) | MCHR1MEN1POLBKMT2AHTR2C | |
| SCHEMBL19365749 | 0.76 | CA2 (0.42) | GAAMEN1POLBKMT2ATRPV1 | |
| SCHEMBL17623988 | 0.75 | NPC1 (0.37) | GAAMEN1KMT2AGRIN2BHTR2C | |
| SCHEMBL19365246 | 0.75 | MAPT (0.44) | MCHR1GAAMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765075-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-09-19 | — | — | US | disclosed |