Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 5/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | UBE2M | P61081 | 3/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 4/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19365749 | 0.84 | CA2 (0.42) | CHRM3MEN1MAPTKMT2ABRAF | |
| SCHEMBL19670249 | 0.83 | CA2 (0.42) | CHRM3FAAHBRAF | |
| SCHEMBL17623988 | 0.83 | NPC1 (0.37) | CHRM3UBE2MDCUN1D1MEN1MAPT | |
| SCHEMBL19364921 | 0.82 | KIF18A (0.38) | CHRM3UBE2MDCUN1D1MEN1MAPT | |
| SCHEMBL19365407 | 0.81 | MEN1 (0.49) | MEN1KMT2A | |
| SCHEMBL19670123 | 0.81 | TRPA1 (0.37) | CHRM3CNR2TRPV4MAPTBRAF | |
| SCHEMBL19670572 | 0.81 | LMNA (0.35) | MAPTKMT2A | |
| SCHEMBL19365805 | 0.81 | BRAF (0.41) | MEN1MAPTKMT2ABRAFMAPK14 | |
| SCHEMBL19865068 | 0.80 | CHRM3 (0.46) | CHRM3FAAHCNR2UBE2MDCUN1D1 | |
| SCHEMBL19365573 | 0.79 | CA2 (0.39) | CHRM3TRPV4MAPTBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765075-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-09-19 | — | — | US | disclosed |