Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 6/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26003508 | 0.88 | AKR1C3 (0.35) | SCN9ANOTUMAKR1C3KCNH2NAMPT | |
| SCHEMBL19370702 | 0.86 | ESR2 (0.41) | DRD2 | |
| SCHEMBL19370652 | 0.83 | HSD17B3 (0.37) | BAZ2BHSD17B3NAMPT | |
| SCHEMBL19370821 | 0.81 | ESR1 (0.44) | SCN9ADRD2NOTUMAKR1C3NAMPT | |
| SCHEMBL25997931 | 0.78 | KRAS (0.36) | SCN9ANOTUMAKR1C3KCNH2NAMPT | |
| SCHEMBL19370874 | 0.76 | NOTUM (0.39) | NOTUMKCNH2NAMPT | |
| SCHEMBL27113705 | 0.72 | MMP1 (0.33) | DRD2 | |
| SCHEMBL27122248 | 0.69 | HRH3 (0.40) | POLB | |
| SCHEMBL9963388 | 0.68 | ASIC3 (0.48) | ACACBNOTUMHSD17B3AKR1C3KCNH2 | |
| SCHEMBL12383470 | 0.68 | HTR2A (0.41) | DRD2ACACBNOTUMAKR1C3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017161119-A1 | SMALL MOLECULES AGAINST CEREBLON TO ENHANCE EFFECTOR T CELL FUNCTION | H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE, INC. (US) | 2017-09-21 | — | — | WO | disclosed |