Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.33 |
| ▸ | MMP3 | P08254 | 3/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | MC3R | P41968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25997931 | 0.81 | KRAS (0.36) | DPP9 | |
| SCHEMBL27120419 | 0.81 | S1PR1 (0.31) | S1PR1 | |
| SCHEMBL27122248 | 0.76 | HRH3 (0.40) | — | |
| SCHEMBL25986948 | 0.75 | NPC1 (0.31) | — | |
| SCHEMBL26003508 | 0.72 | AKR1C3 (0.35) | DPP9 | |
| SCHEMBL25938420 | 0.72 | BTK (0.33) | — | |
| SCHEMBL25988966 | 0.72 | MEN1 (0.39) | MOGAT2 | |
| SCHEMBL27119016 | 0.71 | S1PR1 (0.31) | S1PR1FAAH | |
| SCHEMBL27119471 | 0.71 | SIGMAR1 (0.33) | S1PR1 | |
| SCHEMBL26022857 | 0.70 | KRAS (0.33) | DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076650-B1 | 3-(5-METHOXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2024-02-28 | — | — | EP | disclosed |