Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1369119 | 0.92 | — | — | |
| SCHEMBL14986913 | 0.92 | — | — | |
| SCHEMBL13971408 | 0.92 | — | — | |
| Ammonia Solution, Strong SCHEMBL27834436 | 0.89 | ALDH1A1 (0.41) | KISS1RALDH1A1TDP1RNPEPSLC7A5 | |
| Diethylamine SCHEMBL27834459 | 0.83 | ALDH1A1 (0.38) | KISS1RALDH1A1TDP1RNPEPSLC7A5 | |
| SCHEMBL12891365 | 0.80 | ALDH1A1 (0.40) | KISS1RALDH1A1TDP1RNPEPSLC7A5 | |
| SCHEMBL17953984 | 0.80 | ALDH1A1 (0.40) | KISS1RALDH1A1TDP1RNPEPSLC7A5 | |
| SCHEMBL18893569 | 0.77 | KISS1R (0.35) | KISS1RALDH1A1TDP1FOLH1NAALAD2 | |
| SCHEMBL16300127 | 0.74 | MMP9 (0.42) | KISS1RRNPEPSLC7A5 | |
| SCHEMBL4660964 | 0.74 | MMP9 (0.42) | KISS1RRNPEPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102120742-B | Preparation method of tetrabenazine | UNIV CHINA PHARMA | 2013-03-13 | — | — | CN | disclosed |
| CN-102120742-A | Preparation method of 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a] quinolizidine-2-ketone | UNIV CHINA PHARMA | 2011-07-13 | — | — | CN | disclosed |
| EP-2331539-A2 | 1,3,4,6,7,11B-HEXAHYDRO-BENZO[ALPHA]QUINOLIZINES FOR THE TREATMENT OF HYPERKINETIC MOVEMENT AND RELATED DISORDERS | Biovail Laboratories International (Barbados) SRL (BB) | 2011-06-15 | — | — | EP | disclosed |
| US-20100087475-A1 | PHARMACEUTICAL COMPOUNDS | Biovali Laboratories International (Barbados) S.R.L. (BB) | 2010-04-08 | — | — | US | disclosed |
| WO-2010026436-A2 | PHARMACEUTICAL COMPOUNDS | BIOVAIL LABORATORIES INTERNATIONAL (BARBADOS) SRL (BB) | 2010-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087475-A1 | PHARMACEUTICAL COMPOUNDS | UGT2B7, CYP3A7, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | KISS1R 4296/4885ALDH1A1 292/4885TDP1 3252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.