SCHEMBL1937375

SCHEMBL1937375

CC(C(=O)c1cccs1)C(=O)c1cccs1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.58
NPC1 O15118 5/20 0.58
ALDH1A1 P00352 4/20 0.58
HPGD P15428 3/20 0.58
CES2 O00748 2/20 0.58
CES1 P23141 2/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
KEAP1 Q14145 1/20 0.58
DAO P14920 1/20 0.56
LMNA P02545 2/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
POLB P06746 1/20 0.52
HDAC1 Q13547 1/20 0.52
CYP2C9 P11712 3/20 0.50
CYP2D6 P10635 1/20 0.50
TSHR P16473 1/20 0.50
CYP2C19 P33261 1/20 0.50
KDM4E B2RXH2 1/20 0.49
PTGS1 P23219 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3839189 0.90 DAO (0.55) RAB9ANPC1ALDH1A1HPGDCES2
SCHEMBL29588329 0.89 HPGDS (0.58) RAB9ANPC1ALDH1A1HPGDCES2
SCHEMBL7163607 0.88 ALDH1A1 (0.51) RAB9ANPC1ALDH1A1HPGDCES2
SCHEMBL11252454 0.88 RAB9A (0.51) RAB9ANPC1ALDH1A1HPGDCES2
SCHEMBL619898 0.87 CES2 (0.64) RAB9ANPC1ALDH1A1HPGDCES2
SCHEMBL11245257 0.87 DAO (0.52) RAB9ANPC1ALDH1A1HPGDCES2
SCHEMBL28843649 0.85 RAB9A (0.49) RAB9ANPC1ALDH1A1HPGDCES2
SCHEMBL15163429 0.85 HPGD (0.56) RAB9ANPC1ALDH1A1HPGDCES2
SCHEMBL23793030 0.85 RAB9A (0.56) RAB9ANPC1ALDH1A1HPGDCES2
SCHEMBL14490190 0.85 CES2 (0.61) RAB9ANPC1ALDH1A1HPGDCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2331600-A1 POLYMERS DERIVED FROM BIS(THIENOCYCLOPENTA)BENZOTHIADIAZOLE AND THEIR USE AS ORGANIC SEMICONDUCTORS Merck Patent GmbH (DE) 2011-06-15 EP disclosed
WO-2010031479-A1 POLYMERS DERIVED FROM BIS(THIENOCYCLOPENTA)BENZOTHIADIAZOLE AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2010-03-25 WO disclosed