Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18834584 | 0.88 | TRPC5 (0.50) | TRPC5MAPT | |
| SCHEMBL18834573 | 0.73 | TRPC5 (0.51) | TRPC5ALDH1A1MAPT | |
| SCHEMBL19375505 | 0.72 | PDE4A (0.33) | LMNAALDH1A1GAA | |
| SCHEMBL19375583 | 0.71 | MAPT (0.37) | TRPC5LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL20432550 | 0.66 | TRPC5 (0.48) | TRPC5 | |
| SCHEMBL17517380 | 0.66 | TRPC5 (0.74) | TRPC5SMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL18834990 | 0.65 | ALDH1A1 (0.48) | TRPC5LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL18834860 | 0.65 | HTT (0.39) | SMN1; SMN2LMNAALDH1A1L3MBTL1MEN1 | |
| SCHEMBL2269932 | 0.65 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAUSP2ALDH1A1GAA | |
| SCHEMBL28015900 | 0.65 | HPGD (0.52) | SMN1; SMN2LMNAUSP2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |