Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 15/20 | 0.41 |
| ▸ | TRPC5 | Q9UL62 | 3/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20432433 | 0.91 | USP1 (0.39) | USP1TRPC5 | |
| SCHEMBL18835271 | 0.79 | MDM2 (0.37) | TRPC5ADORA3 | |
| SCHEMBL18835033 | 0.74 | USP1 (0.39) | USP1TRPC5ADORA3 | |
| SCHEMBL20432139 | 0.74 | PDE5A (0.39) | ADORA3 | |
| SCHEMBL18834415 | 0.71 | ALDH1A1 (0.44) | ADORA3 | |
| SCHEMBL20432208 | 0.71 | PDE5A (0.37) | ADORA3 | |
| SCHEMBL16028775 | 0.70 | TRPC5 (0.54) | TRPC5ADORA3 | |
| SCHEMBL19375150 | 0.69 | USP1 (0.41) | USP1TRPC5 | |
| SCHEMBL21345626 | 0.64 | MEN1 (0.40) | — | |
| SCHEMBL18835410 | 0.64 | PDE5A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |