Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.41 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18834408 | 0.85 | TRPC5 (0.44) | TRPC4TRPC5KCNH2TSHRHTT | |
| SCHEMBL16028570 | 0.82 | TRPC5 (0.59) | TRPC4TRPC5KCNH2SMN1; SMN2TSHR | |
| SCHEMBL19375294 | 0.81 | PDE4A (0.36) | TRPC4TRPC5KCNH2TRPC1ADORA3 | |
| SCHEMBL16027686 | 0.81 | ADORA3 (0.55) | TRPC4TRPC5KCNH2SMN1; SMN2TSHR | |
| SCHEMBL19375019 | 0.77 | TRPC4 (0.42) | TRPC4TRPC5KCNH2SMN1; SMN2TSHR | |
| SCHEMBL16028583 | 0.76 | TRPC5 (0.59) | TRPC4TRPC5KCNH2SMN1; SMN2TSHR | |
| SCHEMBL16364220 | 0.76 | TRPC5 (0.55) | TRPC4TRPC5KCNH2SMN1; SMN2TSHR | |
| SCHEMBL16028388 | 0.75 | TRPC5 (0.57) | TRPC4TRPC5KCNH2SMN1; SMN2TSHR | |
| SCHEMBL16028289 | 0.75 | TRPC5 (0.57) | TRPC4TRPC5KCNH2SMN1; SMN2TRPC1 | |
| SCHEMBL16076147 | 0.74 | TRPC4 (0.50) | TRPC4TRPC5KCNH2SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |