Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 3/20 | 0.40 |
| ▸ | CDK4 | P11802 | 3/20 | 0.40 |
| ▸ | CCND1 | P24385 | 3/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 3/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936059 | 0.89 | PRMT5 (0.41) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL14324623 | 0.80 | TP53 (0.40) | DHODHABL1ABCB1BCRMEN1 | |
| SCHEMBL1937723 | 0.78 | ABL1 (0.38) | DHODHTEKABL1ABCB1BCR | |
| SCHEMBL1937496 | 0.78 | ABL1 (0.38) | DHODHTEKABL1ABCB1BCR | |
| SCHEMBL1937699 | 0.77 | ABL1 (0.37) | DHODHTEKABL1ABCB1BCR | |
| SCHEMBL1937991 | 0.73 | ABL1 (0.39) | DHODHTEKABL1ABCB1BCR | |
| SCHEMBL2348136 | 0.72 | DRD1 (0.43) | GSK3AGSK3BDYRK1ANPC1RAB9A | |
| SCHEMBL17514802 | 0.71 | ALDH1A1 (0.48) | ABL1ABCB1BCR | |
| SCHEMBL1560182 | 0.71 | NPC1 (0.41) | TEKABL1ABCB1BCRNPC1 | |
| SCHEMBL1937701 | 0.70 | TP53 (0.36) | TEKABL1ABCB1BCRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2330891-A1 | FUNGICIDAL PYRIDAZINES | E. I. du Pont de Nemours and Company (US) | 2011-06-15 | — | — | EP | disclosed |
| US-20110136762-A1 | FUNGICIDAL PYRIDAZINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-06-09 | — | — | US | disclosed |
| WO-2010036553-A1 | FUNGICIDAL PYRIDAZINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136762-A1 | FUNGICIDAL PYRIDAZINES | PRDX1, PNPO, PRXL2A | CCNE2 1585/4885CDK4 2298/4885CCND1 1174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.