Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | USP1 | O94782 | 1/20 | 0.36 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.36 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.36 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.36 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19375271 | 0.81 | TRPC5 (0.36) | TRPC5P2RX3CHRM5LMNAMAPT | |
| SCHEMBL19375117 | 0.77 | PDE5A (0.36) | TRPC5TRPC1TRPC4MAPTACHE | |
| SCHEMBL19375040 | 0.76 | RAB9A (0.36) | P2RX3LMNAMAPTTP53ACHE | |
| SCHEMBL19375187 | 0.75 | TRPC4 (0.44) | TRPC5TRPC1TRPC4P2RX3SCN9A | |
| SCHEMBL16076074 | 0.74 | TRPC5 (0.59) | TRPC5TRPC1TRPC4LMNAMAPT | |
| SCHEMBL19375632 | 0.70 | PDE5A (0.35) | USP1TRPC5TRPC1TRPC4P2RX3 | |
| SCHEMBL19375219 | 0.70 | TRPC4 (0.46) | TRPC5TRPC1TRPC4P2RX3 | |
| SCHEMBL19375380 | 0.69 | MEN1 (0.41) | MDM2P2RX3 | |
| SCHEMBL18835220 | 0.69 | DPP4 (0.37) | MDM2SCN9ASCN5ACHRM5HSD11B1 | |
| SCHEMBL16028967 | 0.68 | TRPC5 (0.58) | TRPC5TRPC1TRPC4LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |