Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19375040 | 0.89 | RAB9A (0.36) | LMNAKDM4EHTTALDH1A1MAPT | |
| SCHEMBL19375500 | 0.81 | MDM2 (0.37) | TRPC5LMNAMAPTP2RX3TP53 | |
| SCHEMBL20432562 | 0.80 | PDE5A (0.45) | TRPC5LMNAALDH1A1MAPTP2RX3 | |
| SCHEMBL19375632 | 0.79 | PDE5A (0.35) | TRPC5P2RX3KMT2APDE5A | |
| SCHEMBL19375494 | 0.74 | TRPC4 (0.43) | TRPC5ALDH1A1ADORA3P2RX3PDE5A | |
| SCHEMBL30171280 | 0.73 | TRPC5 (0.55) | TRPC5NPSR1LMNAHTTALDH1A1 | |
| SCHEMBL16076061 | 0.73 | TRPC5 (0.55) | TRPC5NPSR1LMNAHTTALDH1A1 | |
| SCHEMBL20432067 | 0.72 | HSD11B1 (0.40) | KDM4EHTTALDH1A1KMT2A | |
| SCHEMBL19375187 | 0.71 | TRPC4 (0.44) | TRPC5LMNAHTTALDH1A1MAPT | |
| SCHEMBL19375544 | 0.71 | ADORA3 (0.35) | NPSR1LMNAHTTALDH1A1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |