Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 19/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.33 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20432382 | 0.91 | TRPC5 (0.40) | P2RX3KCNH2TRPC4TRPC5 | |
| SCHEMBL21316297 | 0.89 | TRPC4 (0.42) | P2RX3KCNH2TRPC4TRPC5 | |
| SCHEMBL18834916 | 0.85 | TRPC4 (0.45) | P2RX3KCNH2TRPC4TRPC5 | |
| SCHEMBL21499681 | 0.84 | P2RX3 (0.40) | P2RX3KCNH2TRPC4TRPC5 | |
| SCHEMBL18834470 | 0.82 | TRPC5 (0.35) | P2RX3TRPC5 | |
| SCHEMBL20432022 | 0.81 | TRPC4 (0.42) | P2RX3KCNH2TRPC4TRPC5 | |
| SCHEMBL19505572 | 0.81 | TRPC4 (0.47) | P2RX3KCNH2TRPC4TRPC5 | |
| SCHEMBL21499674 | 0.80 | TRPC4 (0.41) | P2RX3KCNH2TRPC4TRPC5 | |
| SCHEMBL18834542 | 0.80 | P2RX3 (0.31) | P2RX3 | |
| SCHEMBL19505249 | 0.79 | TRPC5 (0.49) | P2RX3KCNH2TRPC4TRPC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |