Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18834470 | 0.92 | TRPC5 (0.35) | P2RX3CNR1TSHRALDH1A1GAA | |
| SCHEMBL21499708 | 0.85 | COMT (0.33) | P2RX3TSHRMDM2ALDH1A1 | |
| SCHEMBL19505043 | 0.84 | TRPC5 (0.37) | P2RX3MDM2ALDH1A1GAA | |
| SCHEMBL19375039 | 0.83 | RAB9A (0.36) | P2RX3TSHRTP53MDM2ALDH1A1 | |
| SCHEMBL18834622 | 0.81 | P2RX3 (0.35) | P2RX3 | |
| SCHEMBL19375606 | 0.80 | P2RX3 (0.37) | P2RX3 | |
| SCHEMBL18835240 | 0.79 | TRPC5 (0.47) | P2RX3 | |
| SCHEMBL18834975 | 0.78 | KDM4E (0.39) | CNR1TSHRALDH1A1GAA | |
| SCHEMBL20432382 | 0.76 | TRPC5 (0.40) | P2RX3 | |
| SCHEMBL20432069 | 0.75 | TRPC5 (0.36) | P2RX3CNR1TSHRTP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |