Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 16/20 | 0.43 |
| ▸ | EDNRB | P24530 | 10/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1938691 | 0.89 | EDNRA (0.38) | EDNRAEDNRB | |
| SCHEMBL1162420 | 0.82 | PTGS2 (0.46) | EDNRAEDNRBPTGS2PGR | |
| SCHEMBL2353756 | 0.74 | PTGS2 (0.53) | EDNRAEDNRBPTGS2 | |
| SCHEMBL1162485 | 0.70 | PTGS2 (0.46) | EDNRAEDNRBPTGS2ALDH1A1 | |
| SCHEMBL2351267 | 0.69 | PTGS2 (0.55) | PTGS2 | |
| SCHEMBL3337047 | 0.67 | PTGS2 (0.58) | PTGS2ALDH1A1 | |
| SCHEMBL14324010 | 0.67 | EDNRA (0.34) | EDNRAEDNRBEGFRALDH1A1 | |
| SCHEMBL2354428 | 0.66 | PTGS2 (0.61) | PTGS2PGR | |
| SCHEMBL1937718 | 0.66 | PTGS2 (0.60) | EDNRAEDNRBPTGS2 | |
| SCHEMBL1162763 | 0.66 | PTGS2 (0.34) | PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2330891-A1 | FUNGICIDAL PYRIDAZINES | E. I. du Pont de Nemours and Company (US) | 2011-06-15 | — | — | EP | disclosed |
| US-20110136762-A1 | FUNGICIDAL PYRIDAZINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-06-09 | — | — | US | disclosed |
| WO-2010036553-A1 | FUNGICIDAL PYRIDAZINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136762-A1 | FUNGICIDAL PYRIDAZINES | PRDX1, PNPO, PRXL2A | EDNRA 1243/4885EDNRB 1462/4885EGFR 4165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.