Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 8/20 | 0.44 |
| ▸ | KCNA1 | Q09470 | 4/20 | 0.44 |
| ▸ | KCNAB1 | Q14722 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19377150 | 1.00 | TRIM24 (0.44) | TRIM24KCNA1KCNAB1LMNAMAPK1 | |
| SCHEMBL19377098 | 0.91 | DRD2 (0.49) | TRIM24KCNA1KCNAB1LMNAMAPK1 | |
| SCHEMBL19377102 | 0.91 | DRD2 (0.49) | TRIM24KCNA1KCNAB1LMNAMAPK1 | |
| SCHEMBL19377120 | 0.89 | LMNA (0.41) | TRIM24KCNA1KCNAB1LMNAMAPK1 | |
| SCHEMBL19377122 | 0.89 | LMNA (0.41) | TRIM24KCNA1KCNAB1LMNAMAPK1 | |
| SCHEMBL19377389 | 0.89 | ABCB1 (0.43) | TRIM24KCNA1KCNAB1LMNAMAPK1 | |
| SCHEMBL19377390 | 0.89 | ABCB1 (0.43) | TRIM24KCNA1KCNAB1LMNAMAPK1 | |
| SCHEMBL19377117 | 0.87 | ACACB (0.40) | TRIM24KCNA1KCNAB1ALDH1A1CYP2C9 | |
| SCHEMBL19377118 | 0.87 | ACACB (0.40) | TRIM24KCNA1KCNAB1ALDH1A1CYP2C9 | |
| SCHEMBL19377509 | 0.83 | PNMT (0.43) | LMNAMAPK1HTTALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170275301-A1 | Benzenesulfonyl-Asymmetric Ureas and Medical Uses Thereof | HELSINN HEALTHCARE SA (CH) | 2017-09-28 | — | — | US | claimed |
| US-20170275301-A1 | Benzenesulfonyl-Asymmetric Ureas and Medical Uses Thereof | HELSINN HEALTHCARE SA (CH) | 2017-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170275301-A1 | Benzenesulfonyl-Asymmetric Ureas and Medical Uses Thereof | UTS2R, GHSR, GRPR | TRIM24 4395/4885KCNA1 4711/4885KCNAB1 4197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.