Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.50 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMO | Q99835 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1514283 | 0.77 | HPGD (0.77) | HPGDCYP1A2CYP2C19RAB9APOLB | |
| SCHEMBL9833874 | 0.77 | CYP1A2 (0.77) | HPGDCYP1A2CYP2C19RAB9APOLB | |
| SCHEMBL8243220 | 0.76 | NPC1 (0.36) | HPGDCYP1A2CYP2C19RAB9AMAPT | |
| SCHEMBL31680566 | 0.76 | CYP1A2 (0.89) | HPGDCYP1A2CYP2C19RAB9APOLB | |
| SCHEMBL14890169 | 0.76 | CYP1A2 (0.74) | HPGDCYP1A2CYP2C19RAB9APOLB | |
| SCHEMBL20385118 | 0.75 | ALDH1A1 (0.48) | HPGDCYP1A2CYP2C19PABPC1EIF4H | |
| SCHEMBL13212290 | 0.74 | CYP1A2 (0.72) | HPGDCYP1A2CYP2C19RAB9APOLB | |
| SCHEMBL6357071 | 0.73 | PTGES (0.76) | HPGDCYP1A2CYP2C19RAB9APOLB | |
| SCHEMBL8279069 | 0.72 | HPGD (0.68) | HPGDCYP1A2CYP2C19RAB9APOLB | |
| SCHEMBL28636438 | 0.72 | KDM4E (0.74) | HPGDCYP1A2CYP2C19RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017157882-A1 | SERINE BIOSYNTHETIC PATHWAY INHIBITORS | Université Catholique de Louvain (BE) | 2017-09-21 | — | — | WO | disclosed |