Tetrahydrofuran

Tetrahydrofuran

SCHEMBL1938419

C1CCOC1.CC(=O)OC(C)=O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.56
▸ TSHR P16473 3/20 0.56
▸ HSD17B10 Q99714 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ SMN1; SMN2 Q16637 3/20 0.37
▸ KDM4E B2RXH2 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ TP53 P04637 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ GLA P06280 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ POLB P06746 1/20 0.31
▸ USP2 O75604 1/20 0.30
▸ PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL4337006 1.00 ALDH1A1 (0.56) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
Dioxane SCHEMBL9508711 0.88 ALDH1A1 (0.62) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
Oxirane SCHEMBL8581231 0.85 ALDH1A1 (0.67) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
SCHEMBL28288392 0.84 ALDH1A1 (0.50) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
Tetrahydrofuran SCHEMBL10761380 0.83 ALDH1A1 (0.56) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
SCHEMBL9508706 0.83 ALDH1A1 (0.56) ALDH1A1TSHRHSD17B10TDP1
Tetrahydrofuran SCHEMBL165529 0.82 — —
Pyridine SCHEMBL15233785 0.82 TSHR (0.37) ALDH1A1TSHRTDP1MEN1KMT2A
Tetrahydrofuran SCHEMBL29171726 0.81 ALDH1A1 (0.53) ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2
Tetrahydrofuran SCHEMBL28969290 0.80 ALDH1A1 (0.54) ALDH1A1TSHRSMN1; SMN2GLALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112645994-B Extraction process of salidroside 湖州柳荫生物科技有限公司 2022-08-26 — — CN claimed
CN-112645994-A Extraction process of salidroside 湖州柳荫生物科技有限公司 2021-04-13 — — CN claimed
CN-103408554-A Hypertensive activity reducing pyrrole coumarins compound and preparation method thereof UNIV XI AN JIAOTONG 2013-11-27 — — CN claimed
WO-2024143276-A1 OLIGONUCLEOTIDE PRODUCTION METHOD 住友化学株式会社 2024-07-04 — — WO disclosed
CN-113677432-B Inorganic porous carrier and method for producing nucleic acid using same 住友化学株式会社 2024-06-07 — — CN disclosed
CN-118147134-A SiRNA for targeted regulation and control of PCSK9 gene expression and application thereof 北京悦康科创医药科技股份有限公司 2024-06-07 — — CN disclosed
CN-113646083-B Inorganic porous carrier and method for producing nucleic acid using same 住友化学株式会社 2024-06-07 — — CN disclosed
CN-118109463-A SiRNA targeting PCSK9 gene and application thereof 北京悦康科创医药科技股份有限公司 2024-05-31 — — CN disclosed
EP-4368627-A1 COMPOSITION CONTAINING NUCLEIC ACID OLIGOMER Sumitomo Chemical Company, Limited (JP) 2024-05-15 — — EP disclosed
CN-117980285-A Process for producing purified dichloroacetic acid 住友化学株式会社 2024-05-03 — — CN disclosed
WO-2024089953-A1 METHOD FOR PRODUCING OLIGONUCLEOTIDE 住友化学株式会社 2024-05-02 — — WO disclosed
CN-1950417-A Polythiourethanes UBE IND LTD A CORP OF JAPAN (JP) 2007-04-18 — — CN disclosed
EP-1180113-A4 OLIGONUCLEOTIDES HAVING A-DNA FORM AND B-DNA FORM CONFORMATIONAL GEOMETRY ISIS PHARMACEUTICALS INC (US) 2002-09-18 — — EP disclosed
EP-1180113-A1 OLIGONUCLEOTIDES HAVING A-DNA FORM AND B-DNA FORM CONFORMATIONAL GEOMETRY ISIS PHARMACEUTICALS, INC. (US) 2002-02-20 — — EP disclosed
WO-2000066609-A1 OLIGONUCLEOTIDES HAVING A-DNA FORM AND B-DNA FORM CONFORMATIONAL GEOMETRY ISIS PHARMACEUTICALS, INC. (US) 2000-11-09 — — WO disclosed
US-6004826-A Repair-mediated process for amplifying and detecting nucleic acid sequences Segev, David 1999-12-21 — — US disclosed
EP-0425563-B1 PROCESS FOR AMPLIFYING AND DETECTING NUCLEIC ACID SEQUENCES SEGEV DAVID (IL) 1996-05-15 — — EP disclosed
EP-0425563-A4 PROCESS FOR AMPLIFYING AND DETECTING NUCLEIC ACID SEQUENCES — 1992-06-10 — — EP disclosed
EP-0425563-A1 PROCESS FOR AMPLIFYING AND DETECTING NUCLEIC ACID SEQUENCES. SEGEV DIAGNOSTICS INC (US) 1991-05-08 — — EP disclosed
WO-1990001069-A1 PROCESS FOR AMPLIFYING AND DETECTING NUCLEIC ACID SEQUENCES SEGEV DIAGNOSTICS, INC. (US) 1990-02-08 — — WO disclosed
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