Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dioxane SCHEMBL9508711 | 0.97 | ALDH1A1 (0.62) | ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL1705171 | 0.91 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2 | |
| Fluoride SCHEMBL27342145 | 0.86 | — | — | |
| Tetrahydrofuran SCHEMBL1938419 | 0.85 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2 | |
| Tetrahydrofuran SCHEMBL4337006 | 0.85 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL523 | 0.82 | — | — | |
| SCHEMBL1331977 | 0.82 | — | — | |
| SCHEMBL9866292 | 0.82 | — | — | |
| SCHEMBL1331774 | 0.82 | — | — | |
| SCHEMBL1330344 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708168-A | FOR TREATING OR PREVENTING NEURONAL LOSS | STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON, EUGENE OREGON (US) | 1998-01-13 | — | — | US | disclosed |
| CN-1036929-C | dispersant for carbon black-filled foam | CELOTEX CORP (US) | 1998-01-07 | — | — | CN | disclosed |
| CN-1069745-A | dispersant for carbon black-filled foam | CELOTEX CORP (US) | 1993-03-10 | — | — | CN | disclosed |