Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxirane SCHEMBL8581231 | 0.97 | ALDH1A1 (0.67) | ALDH1A1TSHRSMN1; SMN2HSD17B10TDP1 | |
| SCHEMBL1705171 | 0.88 | ALDH1A1 (0.56) | ALDH1A1TSHRSMN1; SMN2HSD17B10TDP1 | |
| Tetrahydrofuran SCHEMBL4337006 | 0.88 | ALDH1A1 (0.56) | ALDH1A1TSHRSMN1; SMN2HSD17B10TDP1 | |
| Tetrahydrofuran SCHEMBL1938419 | 0.88 | ALDH1A1 (0.56) | ALDH1A1TSHRSMN1; SMN2HSD17B10TDP1 | |
| Fluoride SCHEMBL27342145 | 0.83 | — | — | |
| Morpholine SCHEMBL28126679 | 0.82 | MEN1 (0.50) | ALDH1A1TSHRSMN1; SMN2HSD17B10TDP1 | |
| Dioxane SCHEMBL11028398 | 0.81 | ALDH1A1 (0.62) | ALDH1A1TSHRSMN1; SMN2HSD17B10KDM4E | |
| Acetone SCHEMBL14359414 | 0.79 | SMN1; SMN2 (0.55) | TSHRSMN1; SMN2HSD17B10KDM4ETTR | |
| Dioxane SCHEMBL1512800 | 0.79 | SMN1; SMN2 (0.55) | TSHRSMN1; SMN2HSD17B10KDM4ETTR | |
| Acetone SCHEMBL5243854 | 0.79 | SMN1; SMN2 (0.55) | TSHRSMN1; SMN2HSD17B10KDM4ETTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104694522-A | Preparation method and application of recombinant acetylation cationoid trypsin | INST RADIATION MED AMMS PLA | 2015-06-10 | — | — | CN | disclosed |
| CN-101687871-A | Spiro condensed barbituric acid derivatives for use as antibacterial | ASTRAZENECA UK LTD | 2010-03-31 | — | — | CN | disclosed |
| EP-0379515-B1 | LOW PRESSURE RHODIUM CATALYZED HYDROFORMYLATION OF OLEFINS | EASTMAN KODAK CO (US) | 1993-10-20 | — | — | EP | disclosed |
| EP-0379515-A1 | LOW PRESSURE RHODIUM CATALYZED HYDROFORMYLATION OF OLEFINS. | EASTMAN KODAK CO (US) | 1990-08-01 | — | — | EP | disclosed |
| US-4873213-A | TRIBENZYLPHOSPHINE COMPLEXES; SELECTIVITY | EASTMAN CHEMICAL COMPANY | 1989-10-10 | — | — | US | disclosed |
| US-4871878-A | HIGH SELECTIVITY TO ALDEHYDES USING AROMATIC PHOSPHINE IN CATALYST | EASTMAN KODAK COMPANY (US) | 1989-10-03 | — | — | US | disclosed |
| WO-1989001467-A1 | LOW PRESSURE RHODIUM CATALYZED HYDROFORMYLATION OF OLEFINS | EASTMAN KODAK COMPANY (US) | 1989-02-23 | — | — | WO | disclosed |