Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19385428 | 0.84 | PRKCA (0.33) | PRKCA | |
| SCHEMBL445609 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TSHRLMNAHSD17B10 | |
| SCHEMBL445367 | 0.75 | HDAC1 (0.37) | PRKCAALDH1A1TSHRLMNAHSD17B10 | |
| SCHEMBL33456 | 0.72 | — | — | |
| SCHEMBL443489 | 0.72 | PRKCA (0.38) | PRKCAMAPK1ALDH1A1TSHRLMNA | |
| SCHEMBL3664713 | 0.70 | PRKCA (0.47) | PRKCATSHRLMNA | |
| Acetic Acid SCHEMBL27418791 | 0.70 | TSHR (0.36) | PRKCAMAPTALDH1A1TSHRLMNA | |
| SCHEMBL8947462 | 0.70 | PRKCA (0.33) | PRKCA | |
| SCHEMBL9452810 | 0.70 | — | — | |
| SCHEMBL19511744 | 0.69 | TSHR (0.33) | ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017164750-A1 | THERAPEUTIC COMPOSITIONS AND USES THEREOF | MANUKA HEALTH NEW ZEALAND LIMITED (NZ) | 2017-09-28 | — | — | WO | disclosed |