SCHEMBL19386129

SCHEMBL19386129

O=C(O)/C=C(/CC(=O)C(=O)O)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.68
TSHR P16473 1/20 0.68
OR51E2 Q9H255 2/20 0.35
ERCC5 P28715 3/20 0.33
FEN1 P39748 3/20 0.33
PTPN1 P18031 2/20 0.33
HAO1 Q9UJM8 2/20 0.33
MAPK1 P28482 1/20 0.32
SLC13A3 Q8WWT9 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
ALOX15 P16050 1/20 0.30
HSD17B10 Q99714 1/20 0.30
ABAT P80404 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19386130 1.00 KDM4E (0.68) KDM4ETSHROR51E2ERCC5FEN1
SCHEMBL19379403 1.00 KDM4E (0.68) KDM4ETSHROR51E2ERCC5FEN1
SCHEMBL28942452 0.89 TSHR (0.83) KDM4ETSHREGLN1ALOX15HSD17B10
Aconitic Acid SCHEMBL1289876 0.81 TSHR (1.00) KDM4ETSHRALOX15HSD17B10ABAT
Aconitic Acid SCHEMBL16935 0.81 TSHR (1.00) KDM4ETSHRALOX15HSD17B10ABAT
Aconitic Acid SCHEMBL2022211 0.81 TSHR (1.00) KDM4ETSHRALOX15HSD17B10ABAT
Aconitic Acid SCHEMBL22334 0.81 TSHR (1.00) KDM4ETSHRALOX15HSD17B10ABAT
Aconitic Acid SCHEMBL219037 0.81 TSHR (1.00) KDM4ETSHRALOX15HSD17B10ABAT
Aconitic Acid SCHEMBL1275978 0.81 TSHR (1.00) KDM4ETSHRALOX15HSD17B10ABAT
SCHEMBL16553219 0.80 KDM4E (0.56) KDM4ETSHRALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017165689-A2 CONVERSION OF BIOMASS TO USEFUL INTERMEDIATES ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2017-09-28 WO disclosed