⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29196007 | 0.68 | — | — | |
| SCHEMBL28454898 | 0.67 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL3100514 | 0.61 | — | — | |
| SCHEMBL1496507 | 0.61 | — | — | |
| SCHEMBL18856537 | 0.55 | ALDH1A1 (0.32) | — | |
| SCHEMBL7478363 | 0.55 | — | — | |
| SCHEMBL365160 | 0.54 | — | — | |
| P-Xylene SCHEMBL9492886 | 0.46 | ACHE (0.62) | — | |
| SCHEMBL272478 | 0.46 | NLRP3 (0.36) | — | |
| SCHEMBL28996979 | 0.46 | NLRP3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250009723-A1 | MANNOSE-DERIVED ANTAGONISTS OF FIMH USEFUL FOR TREATING DISEASE | FIMBRION THERAPEUTICS, INC. | 2025-01-09 | — | — | US | disclosed |
| US-20220235087-A1 | MANNOSE-DERIVED ANTAGONISTS OF FIMH USEFUL FOR TREATING DISEASE | FIMBRION THERAPEUTICS, INC. | 2022-07-28 | — | — | US | disclosed |
| US-20200407390-A1 | MANNOSE-DERIVED ANTAGONISTS OF FIMH USEFUL FOR TREATING DISEASE | FIMBRION THERAPEUTICS INC (US) | 2020-12-31 | — | — | US | disclosed |
| US-10738070-B2 | Mannose-derived antagonists of FimH useful for treating disease | FIMBRION THERAPEUTICS, INC. (US) | 2020-08-11 | — | — | US | disclosed |
| US-20190106451-A1 | MANNOSE-DERIVED ANTAGONISTS OF FIMH USEFUL FOR TREATING DISEASE | CLIMATE LLC | 2019-04-11 | — | — | US | disclosed |
| EP-3432892-A1 | MANNOSE-DERIVED ANTAGONISTS OF FIMH USEFUL FOR TREATING DISEASE | Fimbrion Therapeutics, Inc. (US) | 2019-01-30 | — | — | EP | disclosed |
| WO-2017165619-A1 | MANNOSE-DERIVED ANTAGONISTS OF FIMH USEFUL FOR TREATING DISEASE | FIMBRION THERAPEUTICS, INC. (US) | 2017-09-28 | — | — | WO | disclosed |