Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.40 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16264765 | 0.89 | PDGFRB (0.44) | DRD2DRD3DRD4NPC1MAPT | |
| SCHEMBL18625959 | 0.83 | NAMPT (0.43) | DRD2DRD3DRD4NPC1MAPT | |
| SCHEMBL16263160 | 0.83 | NPC1 (0.42) | DRD2DRD3DRD4NPC1MAPT | |
| SCHEMBL22110466 | 0.83 | DRD2 (0.56) | DRD2DRD3DRD4NPC1MAPT | |
| SCHEMBL18625982 | 0.83 | NPC1 (0.40) | DRD2DRD3DRD4NPC1MAPT | |
| SCHEMBL12022152 | 0.77 | CYP19A1 (0.62) | NPC1RAB9AMEN1KMT2A | |
| Bromide SCHEMBL1883296 | 0.75 | CYP19A1 (0.60) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL17697510 | 0.74 | CYP19A1 (0.58) | DRD2DRD3DRD4NPC1RAB9A | |
| SCHEMBL29009129 | 0.74 | CA12 (0.46) | NPC1MAPTRAB9AALDH1A1PDGFRB | |
| SCHEMBL30434942 | 0.74 | CA12 (0.46) | NPC1MAPTRAB9AALDH1A1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9771389-B2 | Tylosin derivatives and method for preparation thereof | THE KITASAKO INSTITUTE (JP) | 2017-09-26 | — | — | US | disclosed |