Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 2/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18625959 | 0.89 | NAMPT (0.43) | NPC1MAPTRAB9AALDH1A1PDGFRB | |
| SCHEMBL16264765 | 0.85 | PDGFRB (0.44) | NPC1MAPTRAB9AALDH1A1PDGFRB | |
| SCHEMBL19387101 | 0.83 | DRD2 (0.43) | NPC1MAPTRAB9AALDH1A1PDGFRB | |
| SCHEMBL18625977 | 0.79 | CYP19A1 (0.55) | NPC1RAB9AMGAMGAASI | |
| SCHEMBL16263160 | 0.79 | NPC1 (0.42) | NPC1MAPTRAB9AALDH1A1PDGFRB | |
| SCHEMBL29009129 | 0.70 | CA12 (0.46) | NPC1MAPTRAB9AALDH1A1PDGFRB | |
| SCHEMBL30434942 | 0.70 | CA12 (0.46) | NPC1MAPTRAB9AALDH1A1PDGFRB | |
| SCHEMBL23386949 | 0.70 | GPR55 (0.57) | ALDH1A1MGAMGAASIMGAM2 | |
| SCHEMBL22110466 | 0.67 | DRD2 (0.56) | NPC1MAPTRAB9AMETDRD2 | |
| SCHEMBL30434559 | 0.66 | PDGFRB (0.46) | NPC1MAPTRAB9AALDH1A1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593140-B2 | Antibacterial tylosin derivatives and methods for their preparation | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-03-14 | — | — | US | disclosed |