Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.33 |
| ▸ | ABAT | P80404 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3559017 | 0.76 | MAOA (0.42) | CA2CA1CA12CA9PTGS2 | |
| SCHEMBL31727287 | 0.74 | PDIA6 (0.49) | CA2CA1CA12CA9PDIA6 | |
| SCHEMBL20052097 | 0.71 | UNG (0.42) | KDM4EPTGS2RAB9AALDH1A1TDP1 | |
| SCHEMBL5679972 | 0.71 | CISD1 (0.37) | CA2CA1CA12CA9KDM4E | |
| SCHEMBL23200538 | 0.70 | ALDH1A1 (0.42) | CA2CA1CA12CA9KDM4E | |
| SCHEMBL13044803 | 0.70 | ALDH1A1 (0.55) | CA2CA1CA12CA9KDM4E | |
| SCHEMBL18231235 | 0.70 | CA1 (0.43) | CA2CA1CA12CA9KDM4E | |
| SCHEMBL31726251 | 0.70 | TYR (0.41) | CA2CA1CA12CA9KDM4E | |
| SCHEMBL23201069 | 0.70 | ALDH1A1 (0.59) | CA2CA1CA12CA9PTGS2 | |
| SCHEMBL2646831 | 0.69 | ESR1 (0.52) | KDM4EALDH1A1ALDH1A3HPGDALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943603-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-9771345-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2017-09-26 | — | — | US | disclosed |