Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 8/20 | 0.41 |
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.39 |
| ▸ | ITGAV | P06756 | 5/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.39 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.39 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3134109 | 0.94 | PSMB11 (0.46) | F2F10PLGPLAUST14 | |
| SCHEMBL2507635 | 0.91 | F2 (0.44) | F2F10PLGPLAUST14 | |
| SCHEMBL19381919 | 0.83 | MGLL (0.40) | F2F10PLGPLAUST14 | |
| SCHEMBL19382404 | 0.80 | PSMB5 (0.53) | F2F10PLGPLAUST14 | |
| SCHEMBL3143565 | 0.80 | PSMB5 (0.53) | F2F10PLGPLAUST14 | |
| SCHEMBL13380914 | 0.79 | PSMB5 (0.49) | F2MMP2MMP9PSMB11PSMA7 | |
| SCHEMBL2512498 | 0.77 | PSMB5 (0.50) | F2F10PLGPLAUST14 | |
| SCHEMBL19387801 | 0.77 | PSMB5 (0.45) | F2F10PLGPLAUST14 | |
| SCHEMBL19687309 | 0.75 | ALDH1A1 (0.42) | F2F10PLGPLAUST14 | |
| SCHEMBL3149645 | 0.73 | PSMB5 (0.51) | F2F10PLGPLAUST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9771381-B2 | Derivatives of 1-amino-2-cyclobutylethylboronic acid | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-09-26 | — | — | US | disclosed |