Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 10/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 7/20 | 0.45 |
| ▸ | PSMB9 | P28065 | 7/20 | 0.45 |
| ▸ | PSMB6 | P28072 | 7/20 | 0.45 |
| ▸ | PSMB10 | P40306 | 7/20 | 0.45 |
| ▸ | PSMB11 | A5LHX3 | 6/20 | 0.45 |
| ▸ | PSMA7 | O14818 | 6/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 6/20 | 0.45 |
| ▸ | PSMA1 | P25786 | 6/20 | 0.45 |
| ▸ | PSMA2 | P25787 | 6/20 | 0.45 |
| ▸ | PSMA3 | P25788 | 6/20 | 0.45 |
| ▸ | PSMA4 | P25789 | 6/20 | 0.45 |
| ▸ | PSMA5 | P28066 | 6/20 | 0.45 |
| ▸ | PSMB4 | P28070 | 6/20 | 0.45 |
| ▸ | LONP1 | P36776 | 6/20 | 0.45 |
| ▸ | PSMB3 | P49720 | 6/20 | 0.45 |
| ▸ | PSMB2 | P49721 | 6/20 | 0.45 |
| ▸ | PSMA6 | P60900 | 6/20 | 0.45 |
| ▸ | PSMA8 | Q8TAA3 | 6/20 | 0.45 |
| ▸ | PSMB7 | Q99436 | 6/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3148761 | 0.92 | PSMB5 (0.54) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL12225587 | 0.89 | PSMB5 (0.51) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL16459581 | 0.83 | F2 (0.48) | F2ST14TMPRSS6F10PLG | |
| SCHEMBL19687309 | 0.80 | ALDH1A1 (0.42) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL16459579 | 0.80 | CTSL (0.43) | F2ST14TMPRSS6F10PLG | |
| SCHEMBL19387844 | 0.77 | F2 (0.44) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL19686572 | 0.75 | PSMB5 (0.49) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL19387845 | 0.75 | PSMB5 (0.70) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL13380914 | 0.74 | PSMB5 (0.49) | PSMB5PSMB8PSMB9PSMB6PSMB10 | |
| SCHEMBL3148972 | 0.72 | NPY5R (0.56) | PSMB5PSMB8PSMB9PSMB6PSMB10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9771381-B2 | Derivatives of 1-amino-2-cyclobutylethylboronic acid | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-09-26 | — | — | US | disclosed |