Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 7/20 | 0.38 |
| ▸ | CA1 | P00915 | 7/20 | 0.38 |
| ▸ | CA2 | P00918 | 7/20 | 0.38 |
| ▸ | CA9 | Q16790 | 7/20 | 0.38 |
| ▸ | CA7 | P43166 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20314687 | 0.81 | PTPRZ1 (0.67) | PTPRZ1LMNASMN1; SMN2MAPK1HTT | |
| SCHEMBL6000294 | 0.80 | PTPRZ1 (1.00) | PTPRZ1PTPN1CA12CA1CA2 | |
| SCHEMBL16479592 | 0.79 | PTPRZ1 (0.63) | PTPRZ1LMNASMN1; SMN2MAPK1HTT | |
| SCHEMBL11507063 | 0.78 | PTPRZ1 (0.61) | PTPRZ1LMNASMN1; SMN2MAPK1HTT | |
| SCHEMBL15803395 | 0.77 | CA12 (0.63) | PTPRZ1LMNASMN1; SMN2MAPK1HTT | |
| SCHEMBL91977 | 0.76 | PTPRZ1 (0.59) | PTPRZ1LMNASMN1; SMN2MAPK1HTT | |
| SCHEMBL17795365 | 0.76 | PTPRZ1 (0.59) | PTPRZ1MAPK1CA12CA1CA2 | |
| SCHEMBL13526773 | 0.75 | PTPRZ1 (0.58) | PTPRZ1SMN1; SMN2MAPK1ALDH1A1KIF11 | |
| SCHEMBL28773158 | 0.75 | LMNA (0.46) | PTPRZ1LMNASMN1; SMN2ALDH1A1CA12 | |
| SCHEMBL14345059 | 0.75 | PKM (0.59) | PTPRZ1LMNASMN1; SMN2MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222688-A1 | FILM-FORMING COMPOSITION CONTAINING CROSSLINKABLE REACTIVE SILICONE | Nissan Chemical Industries, Ltd. (JP) | 2017-09-27 | — | — | EP | disclosed |