SCHEMBL1939337

SCHEMBL1939337

CCC(COC(=O)O)(COC(=O)O)COC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.42
MAPK1 P28482 2/20 0.40
HIF1A Q16665 2/20 0.40
ALDH1A1 P00352 3/20 0.33
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
LMNA P02545 3/20 0.32
HSD17B10 Q99714 2/20 0.32
FFAR3 O14843 1/20 0.32
ALOX15 P16050 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
SOAT1 P35610 1/20 0.31
PIN1 Q13526 1/20 0.31
HTR1A P08908 1/20 0.30
CYP2D6 P10635 1/20 0.30
SCN1A P35498 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9008772 0.88 MAPK1 (0.42) THRBMAPK1HIF1AALDH1A1TP53
SCHEMBL1357290 0.88 MAPK1 (0.42) THRBMAPK1HIF1AALDH1A1TP53
Bicarbonate SCHEMBL10991903 0.86 MAPK1 (0.41) THRBMAPK1HIF1AALDH1A1TP53
SCHEMBL3085643 0.83 MAPK1 (0.46) MAPK1HIF1AALDH1A1TP53CYP3A4
SCHEMBL17117553 0.83 PAM (0.36) THRBALDH1A1LMNAHSD17B10TDP1
SCHEMBL7052314 0.81 ALDH1A1 (0.36) THRBMAPK1HIF1AALDH1A1HSD17B10
Propene SCHEMBL23036014 0.80 ALDH1A1 (0.48) THRBMAPK1HIF1AALDH1A1TP53
SCHEMBL540580 0.79 ALDH1A1 (0.50) THRBMAPK1HIF1AALDH1A1TP53
Methacrylic Acid SCHEMBL7466787 0.78 ALDH1A1 (0.39) THRBMAPK1HIF1AALDH1A1TP53
SCHEMBL26199444 0.78 ALDH1A1 (0.35) THRBMAPK1HIF1AALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3199569-B1 NON ISOCYANATE POLYURETHANE FOAMS FAURECIA SIEGES DAUTOMOBILE (FR) 2021-05-19 EP disclosed
US-10450416-B2 Non isocyanate polyurethane foams FAURECIA INTERIEUR INDUSTRIE (FR) 2019-10-22 US disclosed
US-20170218124-A1 NON ISOCYANATE POLYURETHANE FOAMS FAURECIA INTERIEUR INDUSTRIE (FR) 2017-08-03 US disclosed
EP-3199569-A1 NON ISOCYANATE POLYURETHANE FOAMS FAURECIA Sièges d'Automobile (FR) 2017-08-02 EP disclosed
EP-1899995-B1 MAGNETORHEOLOGICAL LIQUID BASF SE (DE) 2011-06-15 EP disclosed
EP-1899995-A1 MAGNETORHEOLOGICAL LIQUID BASF SE (DE) 2008-03-19 EP disclosed
WO-2007003580-A1 MAGNETORHEOLOGICAL LIQUID BASF AKTIENGESELLSCHAFT (DE) 2007-01-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170218124-A1 NON ISOCYANATE POLYURETHANE FOAMS NOS3, CBR3, MCM3 THRB 4385/4885MAPK1 1110/4885HIF1A 2617/4885
US-10450416-B2 Non isocyanate polyurethane foams NOS3, CBR3, MCM3 THRB 4385/4885MAPK1 1110/4885HIF1A 2617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.