Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
| ▸ | BAD | Q92934 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2057844 | 0.85 | ALDH1A1 (0.56) | NPC1RAB9AALDH1A1MAPTHTT | |
| SCHEMBL19396275 | 0.82 | ALDH1A1 (0.43) | NPC1RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL17624645 | 0.80 | MAPT (0.47) | NPC1RAB9AALDH1A1MAPTHTT | |
| SCHEMBL15905580 | 0.80 | ALDH1A1 (0.41) | NPC1RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL19396273 | 0.79 | ALDH1A1 (0.40) | NPC1RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL12589842 | 0.77 | SCD5 (0.46) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL12589838 | 0.77 | MAPK14 (0.49) | NPC1RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL12589840 | 0.77 | CYP46A1 (0.47) | NPC1RAB9AALDH1A1MAPTLMNA | |
| SCHEMBL19396274 | 0.76 | ALDH1A1 (0.42) | NPC1RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL4926706 | 0.76 | NPC1 (0.62) | NPC1RAB9AALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170273968-A1 | MAO-B INHIBITORS AND REHABILITATION | DART NEUROSCIENCE, LLC | 2017-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170273968-A1 | MAO-B INHIBITORS AND REHABILITATION | MAOB, MAOA, HTR2B | NPC1 3863/4885RAB9A 960/4885ALDH1A1 1300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.