Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 3/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GGT1 | P19440 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17860113 | 0.82 | MMP2 (0.45) | MMP2TLR2MMP9FOLH1MAPT | |
| SCHEMBL24061949 | 0.77 | CYP2D6 (0.48) | MMP2MMP9FOLH1MAPTMMP8 | |
| SCHEMBL3208515 | 0.77 | — | — | |
| SCHEMBL31091273 | 0.74 | MMP2 (0.49) | MMP2MMP9FAAHFOLH1MMP8 | |
| SCHEMBL8517971 | 0.74 | MMP2 (0.49) | MMP2MMP9FAAHFOLH1MMP8 | |
| SCHEMBL28312053 | 0.74 | GGT1 (0.47) | FOLH1SLC6A5GGT1NOD1 | |
| SCHEMBL14770824 | 0.74 | GGT1 (0.47) | FOLH1SLC6A5GGT1NOD1 | |
| SCHEMBL20220900 | 0.72 | TLR2 (0.45) | MMP2TLR2FAAHASAH1SLC6A5 | |
| SCHEMBL1768641 | 0.72 | MMP2 (0.53) | MMP2 | |
| SCHEMBL1768636 | 0.72 | MMP2 (0.53) | MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017162663-A1 | PRODRUGS OF CYTOTOXIC ACTIVE AGENTS HAVING ENZYMATICALLY CLEAVABLE GROUPS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-28 | — | — | WO | disclosed |