SCHEMBL1940331

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2729885	0.88	RXFP1 (0.70)	LMNARXFP1THRBKMT2AALDH1A1
	SCHEMBL2728689	0.85	RXFP1 (0.67)	LMNARXFP1THRBKMT2AALDH1A1
	SCHEMBL13494963	0.85	RXFP1 (0.64)	LMNARXFP1THRBKMT2AALDH1A1
	SCHEMBL1946124	0.83	LMNA (0.61)	LMNARXFP1THRBKMT2AALDH1A1
	SCHEMBL1946121	0.83	LMNA (0.61)	LMNARXFP1THRBKMT2AALDH1A1
	SCHEMBL1949416	0.78	ALDH1A1 (0.48)	LMNARXFP1THRBKMT2AALDH1A1
	SCHEMBL1939779	0.76	LMNA (0.53)	LMNARXFP1KMT2AKDM4EAURKA
	SCHEMBL1940389	0.76	LMNA (0.45)	LMNARXFP1THRBALDH1A1KDM4E
	SCHEMBL1940391	0.76	LMNA (0.45)	LMNARXFP1THRBALDH1A1KDM4E
	SCHEMBL1949965	0.75	LMNA (0.49)	LMNARXFP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.