Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 14/20 | 0.53 |
| ▸ | PCTP | Q9UKL6 | 5/20 | 0.46 |
| ▸ | STARD10 | Q9Y365 | 2/20 | 0.44 |
| ▸ | STARD7 | Q9NQZ5 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19377005 | 0.91 | GHSR (0.53) | GHSRPCTPSTARD10STARD7 | |
| SCHEMBL19377401 | 0.80 | GHSR (0.70) | GHSRPCTP | |
| SCHEMBL19377260 | 0.78 | PCTP (0.46) | GHSRPCTPSTARD10STARD7ALDH1A1 | |
| SCHEMBL11232803 | 0.73 | PCTP (0.59) | PCTPSTARD10ALDH1A1LMNA | |
| SCHEMBL19377037 | 0.73 | GHSR (0.58) | GHSR | |
| SCHEMBL19377338 | 0.72 | GHSR (0.53) | GHSR | |
| SCHEMBL19377337 | 0.72 | GHSR (0.53) | GHSR | |
| SCHEMBL19377387 | 0.71 | GHSR (0.45) | GHSRPCTPSTARD10STARD7 | |
| SCHEMBL24800034 | 0.70 | GHSR (0.50) | GHSRALDH1A1LMNA | |
| SCHEMBL19377430 | 0.68 | GHSR (0.46) | GHSRPCTPSTARD10STARD7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017162390-A1 | BENZENESULFONYL-ASYMMETRIC UREAS AND MEDICAL USES THEREOF | HELSINN HEALTHCARE SA (CH) | 2017-09-28 | — | — | WO | disclosed |