Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19377297 | 0.85 | GHSR (0.47) | GHSRMAPTSMN1; SMN2MAPK1GAA | |
| SCHEMBL19377260 | 0.75 | PCTP (0.46) | GHSRKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL19377387 | 0.74 | GHSR (0.45) | GHSRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL19377147 | 0.73 | POLB (0.52) | GHSRMAPTSMN1; SMN2MAPK1GAA | |
| SCHEMBL24799991 | 0.72 | MAPT (0.42) | MAPTSMN1; SMN2MAPK1GAAKMT2A | |
| SCHEMBL19377494 | 0.72 | MAPT (0.43) | MAPTSMN1; SMN2MAPK1GAAKMT2A | |
| SCHEMBL19377084 | 0.72 | MAPT (0.43) | GHSRMAPTSMN1; SMN2MAPK1GAA | |
| SCHEMBL19377005 | 0.71 | GHSR (0.53) | GHSR | |
| SCHEMBL19406945 | 0.70 | GHSR (0.53) | GHSRLMNAALDH1A1 | |
| SCHEMBL19377430 | 0.69 | GHSR (0.46) | GHSRMAPTSMN1; SMN2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390355-B1 | BENZENESULFONYL-ASYMMETRIC UREAS AND MEDICAL USES THEREOF | HELSINN HEALTHCARE SA (CH) | 2022-12-28 | — | — | EP | disclosed |