Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | PLTP | P55058 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19407312 | 0.91 | L3MBTL1 (0.44) | L3MBTL1USP2PLA2G1BATG4BMEN1 | |
| SCHEMBL19407365 | 0.90 | L3MBTL1 (0.41) | L3MBTL1USP2PLA2G1BATG4BMEN1 | |
| SCHEMBL19407504 | 0.89 | L3MBTL1 (0.44) | L3MBTL1USP2PLA2G1BATG4BMEN1 | |
| SCHEMBL19407320 | 0.88 | L3MBTL1 (0.40) | L3MBTL1USP2PLA2G1BATG4BMEN1 | |
| SCHEMBL19160319 | 0.86 | ROCK2 (0.52) | L3MBTL1USP2PLA2G1BATG4BMEN1 | |
| SCHEMBL19155834 | 0.86 | L3MBTL1 (0.41) | L3MBTL1USP2PLA2G1BATG4BMEN1 | |
| SCHEMBL19407480 | 0.85 | PLTP (0.42) | L3MBTL1USP2PLA2G1BATG4BMEN1 | |
| SCHEMBL19407503 | 0.84 | PLTP (0.41) | L3MBTL1USP2PLA2G1BATG4BMEN1 | |
| SCHEMBL19407327 | 0.84 | L3MBTL1 (0.41) | L3MBTL1USP2PLA2G1BATG4BMEN1 | |
| SCHEMBL879437 | 0.84 | L3MBTL1 (0.46) | L3MBTL1USP2PLA2G1BATG4BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170275296-A1 | THERAPEUTIC AGENT FOR MOTOR DISORDERS | KYOWA KIRIN CO., LTD. (JP) | 2017-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170275296-A1 | THERAPEUTIC AGENT FOR MOTOR DISORDERS | DDT, COMT, SLC6A3 | L3MBTL1 699/4885USP2 3774/4885PLA2G1B 2187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.