Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17106806 | 0.72 | SSTR1 (0.41) | — | |
| SCHEMBL17114318 | 0.72 | SSTR1 (0.41) | — | |
| SCHEMBL17106803 | 0.72 | SSTR1 (0.41) | — | |
| SCHEMBL17131361 | 0.72 | SSTR5 (0.33) | CTSLCTSBCTSK | |
| SCHEMBL19997427 | 0.71 | BCHE (0.41) | BCHE | |
| SCHEMBL19644574 | 0.63 | CTSL (0.36) | BCHECTSLCTSBCTSK | |
| SCHEMBL13391159 | 0.60 | NT5E (0.34) | BCHECTSLCTSBCTSK | |
| SCHEMBL24158036 | 0.59 | BCHE (0.44) | BCHECTSLCTSBCTSK | |
| SCHEMBL19101726 | 0.59 | CTSV (0.39) | BCHECTSLCTSBCTSK | |
| SCHEMBL23047613 | 0.58 | BCHE (0.38) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9777035-B2 | 4′-substituted nucleoside reverse transcriptase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-10-03 | — | — | US | disclosed |