Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.32 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19997427 | 0.70 | BCHE (0.41) | BCHEPDE4DOPRM1OPRL1ALDH1A1 | |
| SCHEMBL24158036 | 0.68 | BCHE (0.44) | BCHEOPRM1OPRL1 | |
| SCHEMBL19292430 | 0.67 | CTSV (0.38) | BCHEALDH1A1 | |
| SCHEMBL19650285 | 0.64 | MAPT (0.38) | BCHEALDH1A1 | |
| SCHEMBL19101726 | 0.63 | CTSV (0.39) | BCHE | |
| SCHEMBL19962794 | 0.62 | BCHE (0.38) | BCHEALDH1A1 | |
| SCHEMBL24645793 | 0.60 | PDE4D (0.49) | BCHEPDE4DSSTR1SSTR2SSTR4 | |
| SCHEMBL4621113 | 0.60 | TSHR (0.44) | OPRM1OPRL1ALDH1A1 | |
| SCHEMBL335356 | 0.60 | TSHR (0.44) | OPRM1OPRL1ALDH1A1 | |
| SCHEMBL19644574 | 0.59 | CTSL (0.36) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3785717-A1 | METHODS FOR TREATING CORONAVIRIDAE INFECTIONS | Gilead Sciences, Inc. (US) | 2021-03-03 | — | — | EP | disclosed |