Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19292430 | 0.73 | CTSV (0.38) | BCHECTSLCTSBCTSKCTSV | |
| SCHEMBL19997427 | 0.71 | BCHE (0.41) | BCHECYP2C19OPRM1OPRL1 | |
| SCHEMBL19101726 | 0.69 | CTSV (0.39) | BCHECTSLCTSBCTSKCTSV | |
| SCHEMBL23047613 | 0.68 | BCHE (0.38) | BCHEOPRM1OPRL1 | |
| SCHEMBL19962794 | 0.68 | BCHE (0.38) | BCHECTSLCTSBCTSKCTSV | |
| SCHEMBL19650285 | 0.68 | MAPT (0.38) | BCHECTSLCTSBCTSKCTSV | |
| SCHEMBL6099668 | 0.67 | TSHR (0.46) | BCHECTSLCTSBCTSKCTSV | |
| SCHEMBL14527725 | 0.66 | TSHR (0.44) | BCHECTSLCTSBCTSKCTSV | |
| SCHEMBL19644574 | 0.65 | CTSL (0.36) | BCHECTSLCTSBCTSKCTSV | |
| SCHEMBL989623 | 0.64 | CTSL (0.50) | CTSLCTSBCTSKCYP2C19OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3785717-B1 | METHODS FOR TREATING CORONAVIRIDAE INFECTIONS | GILEAD SCIENCES INC (US) | 2022-01-05 | — | — | EP | disclosed |