Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 10/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.51 |
| ▸ | AHCY | P23526 | 2/20 | 0.42 |
| ▸ | ADK | P55263 | 3/20 | 0.40 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.40 |
| ▸ | ATG7 | O95352 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19412759 | 0.87 | METTL3 (0.59) | METTL3PRMT5ADK | |
| SCHEMBL17131322 | 0.87 | METTL3 (0.45) | METTL3PRMT5AHCYADKHASPIN | |
| SCHEMBL17114379 | 0.81 | PRMT5 (0.59) | METTL3PRMT5ADK | |
| SCHEMBL17106825 | 0.81 | PRMT5 (0.59) | METTL3PRMT5ADK | |
| SCHEMBL17106705 | 0.81 | METTL3 (0.43) | METTL3PRMT5AHCYADKATG7 | |
| SCHEMBL17114360 | 0.81 | METTL3 (0.43) | METTL3PRMT5AHCYADKATG7 | |
| SCHEMBL8653483 | 0.78 | AHCY (0.65) | AHCY | |
| SCHEMBL19412712 | 0.77 | PRMT5 (0.49) | METTL3PRMT5AHCYADK | |
| SCHEMBL17131301 | 0.74 | ADK (0.51) | METTL3PRMT5AHCYADKCA2 | |
| SCHEMBL19412717 | 0.74 | METTL3 (0.41) | METTL3PRMT5ADKHASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9777035-B2 | 4′-substituted nucleoside reverse transcriptase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-10-03 | — | — | US | disclosed |