Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | RRM1 | P23921 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29264058 | 0.82 | PIM1 (0.56) | PIM1PIM3ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL29264055 | 0.82 | PIM1 (0.56) | PIM1PIM3ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL30561991 | 0.82 | PIM1 (0.56) | PIM1PIM3ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL7859259 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KDM4EL3MBTL1MAPTHPGD | |
| SCHEMBL7859256 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KDM4EL3MBTL1MAPTHPGD | |
| SCHEMBL5415543 | 0.79 | PIM1 (0.81) | PIM1PIM3ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL11391623 | 0.78 | FBP1 (0.50) | ALDH1A1KDM4EMAPTHPGDLMNA | |
| SCHEMBL11391621 | 0.78 | FBP1 (0.50) | ALDH1A1KDM4EMAPTHPGDLMNA | |
| SCHEMBL10551337 | 0.77 | KDM4E (0.49) | ALDH1A1KDM4EL3MBTL1MAPTLMNA | |
| SCHEMBL10551332 | 0.77 | KDM4E (0.49) | ALDH1A1KDM4EL3MBTL1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170281649-A1 | COMPOUNDS AND THERAPEUTIC USES | UNITY BIOTECHNOLOGY, INC. | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170281649-A1 | COMPOUNDS AND THERAPEUTIC USES | TP53, NQO1, SHMT2 | PIM1 2379/4885PIM3 3299/4885ALDH1A1 545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.