Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | RXFP3 | Q9NSD7 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859256 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDGAAKMT2A | |
| SCHEMBL5646738 | 0.83 | LTA4H (0.48) | ALDH1A1KDM4EHPGDGAAKMT2A | |
| SCHEMBL5646742 | 0.83 | LTA4H (0.48) | ALDH1A1KDM4EHPGDGAAKMT2A | |
| SCHEMBL19420159 | 0.81 | PIM1 (0.55) | ALDH1A1KDM4EHPGDGAAKMT2A | |
| SCHEMBL30740811 | 0.79 | PRMT1 (0.58) | ALDH1A1KDM4EHPGDMTNR1AMTNR1B | |
| SCHEMBL29103652 | 0.79 | PRMT1 (0.58) | ALDH1A1KDM4EHPGDMTNR1AMTNR1B | |
| SCHEMBL2537636 | 0.79 | PRMT1 (0.58) | ALDH1A1KDM4EHPGDMTNR1AMTNR1B | |
| SCHEMBL2537633 | 0.79 | PRMT1 (0.58) | ALDH1A1KDM4EHPGDMTNR1AMTNR1B | |
| SCHEMBL1418447 | 0.76 | TRIM24 (0.63) | ALDH1A1KDM4EHPGDMTNR1AMTNR1B | |
| SCHEMBL8129328 | 0.76 | FBP1 (0.54) | ALDH1A1KDM4EHPGDKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801059-B1 | INDOLE DERIVATIVE | DAINIPPON PHARMACEUTICAL CO (JP) | 2001-06-27 | — | — | EP | disclosed |
| US-5817689-A | ADRENERGIC RECEPTOR-STIMULATING AGENT, OBESITY, DIABETES | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| EP-0801059-A1 | INDOLE DERIVATIVE | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1997-10-15 | — | — | EP | disclosed |