Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292735 | 0.83 | TTR (0.43) | L3MBTL1ALDH1A1LMNANPSR1HTT | |
| SCHEMBL22680775 | 0.83 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1LMNANPSR1HTT | |
| SCHEMBL16791810 | 0.82 | ADRA2A (0.47) | L3MBTL1ALDH1A1TAS1R3TAS1R1LMNA | |
| SCHEMBL20868717 | 0.81 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1LMNANPSR1HTT | |
| SCHEMBL20868718 | 0.81 | LMNA (0.42) | L3MBTL1ALDH1A1LMNANPSR1HTT | |
| SCHEMBL19389253 | 0.81 | CYP2D6 (0.56) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL22004342 | 0.79 | TP53 (0.41) | L3MBTL1ALDH1A1LMNANPSR1HTT | |
| SCHEMBL84489 | 0.78 | LPAR1 (0.50) | ALDH1A1HTTMEN1KMT2APOLB | |
| SCHEMBL24119872 | 0.77 | GAA (0.41) | L3MBTL1ALDH1A1LMNANPSR1HTT | |
| SCHEMBL22932512 | 0.77 | PSEN1 (0.37) | L3MBTL1ALDH1A1LMNANPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170283397-A1 | SUBSTITUTED 1-H-INDOL-3-YL-BENZAMIDE AND 1, 1'-BIPHENYL ANALOGS AS HISTONE DEMETHYLASE INHIBITORS | UNIV UTAH RES FOUND (US) | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170283397-A1 | SUBSTITUTED 1-H-INDOL-3-YL-BENZAMIDE AND 1, 1'-BIPHENYL ANALOGS AS HISTONE DEMETHYLASE INHIBITORS | KDM1A, KDM1B, KDM3A | L3MBTL1 240/4885ALDH1A1 456/4885TAS1R3 4423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.