Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20956878 | 0.87 | RPS6KB1 (0.47) | ATMMEN1KMT2AL3MBTL1RPS6KB1 | |
| SCHEMBL19422692 | 0.75 | P4HTM (0.53) | KMT2AL3MBTL1RPS6KB1AKT1KDM4C | |
| SCHEMBL19422707 | 0.75 | KMT2A (0.50) | KMT2AL3MBTL1RPS6KB1AKT1KDM4C | |
| SCHEMBL19422718 | 0.74 | KDM4C (0.62) | ATMKMT2AL3MBTL1RPS6KB1AKT1 | |
| SCHEMBL19422720 | 0.74 | KDM4C (0.53) | RPS6KB1AKT1KDM4CCLK1DYRK1A | |
| SCHEMBL19422706 | 0.72 | KDM4E (0.58) | RPS6KB1KDM4CKDM4E | |
| SCHEMBL20956885 | 0.70 | ASPH (0.46) | RPS6KB1KDM4CHDAC3HDAC1HDAC2 | |
| SCHEMBL19422708 | 0.69 | VNN1 (0.52) | MEN1KMT2ARPS6KB1AKT1KDM4C | |
| SCHEMBL20956866 | 0.68 | KDM4C (0.67) | MEN1KMT2AKDM4CCLK4KDM4E | |
| SCHEMBL19422738 | 0.68 | KDM4C (0.53) | MEN1KMT2AL3MBTL1KDM4CCLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017171421-A1 | NOVEL PYRIMIDINE-4-CARBOXYLIC ACID DERIVATIVE HAVING ANTICANCER ACTIVITY | 한국과학기술연구원 | 2017-10-05 | — | — | WO | disclosed |